It tells a crime story set in the 16th century Seville during an outbreak of the bubonic plague.

- REVIEW: The Plague (S1 E1&2/6) – The Killing Times

Mateo makes Valerio a deal – they will both escape their pasts and seek out the New World. A quick deal with Luis’s contacts gets them both passage on the next boat to America – but unfortunately for Mateo also raises the interest of the Inquisition, who lie in wait to arrest him as a heretic whilst Valerio escapes back to the city.
For the second time in as many days Mateo is offered an ultimatum to save his soul – help the Inquisition find the killer of a prominent merchant.
Celso confirms the man is Ignacio Azuaga, one of the wealthiest merchants in Spain, and simply states Mateo’s freedom can be won by bringing his killer to justice.

...there’s the more curious story of Germàn’s widow and her hidden career as a famous European painter.
Death and money rule everything in this city; we’ve yet to see little of any light in this otherwise dark and foreboding world that’s been well crafted by the production team.

